***** PCModfit Forum *****
Version 7.8 (1st September 2023)
The Non-Compartmental module (NCA) has been further updated in V7.8. There was a minor anomaly in earlier versions, which was noticed by a very astute user, in the NCA graphs only (thanks to Dr Tony Jarman from Category 1 Pharma Consulting Pty Ltd, Australia) wherein; the λz value was shown as a minus value when it should have been positive. None of the numerical results were affected but just the sign of λz values on the graphs! The numerical examples in all sections (including NCA) of the manual have been re-analysed using V7.8 and yield the correct results.
PCModfit runs with Excel 2013/2016/2019/2021/365 and other versions (for Windows 7, 8, 8.1, 10 and 11).
The non-PC version was published in Biopharmaceutics and Drug Disposition Vol. 11, No. 6, 1990, p.477-497. The author has used PCModfit for numerous Phase I and II studies for domestic and international companies.
All of the computer source code has been rewritten since publication to ensure more accuracy and versatility. The program will only run on a local computer - not a network server and each installation has its own unique licence. PCModfit is mentioned as a reference in over 100 publications to date (ca. 60 are shown on the NCA menu item above for information). The instructions for each option are shown on the individual Tabs within the Excel spreadsheet and in the manual.
User licenses are free and so is the new manual (as a PDF file) in the C:\PCModfit V7.8\Manual\ directory (after installation).
The setup program is available from the menu item Download, at the top of this page where some
guidance on installation is provided.